Cell Cycle Checkpoints

ABC-family proteins mediated transport

Advanced glycosylation endproduct receptor signaling

APC/C-mediated degradation of cell cycle proteins

Apoptotic execution phase

Asparagine N-linked glycosylation

Axon guidance

Base Excision Repair

Bile acid and bile salt metabolism

Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs)

Biological oxidations

Cell Cycle, Mitotic

Cell junction organization

Cell surface interactions at the vascular wall

Cholesterol biosynthesis

Chromosome Maintenance

Circadian Clock

Complement cascade

Costimulation by the CD28 family

Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels

Dissolution of Fibrin Clot

DNA Damage Bypass

DNA Damage Reversal

DNA Repair

DNA Replication

Double-Strand Break Repair

DSCAM interactions

Effects of PIP2 hydrolysis

Eukaryotic Translation Elongation

Eukaryotic Translation Initiation

Eukaryotic Translation Termination

Extrinsic Pathway for Apoptosis

Factors involved in megakaryocyte development and platelet production

Fanconi Anemia pathway

Fatty acid, triacylglycerol, and ketone body metabolism

Formation of Fibrin Clot (Clotting Cascade)

Gap junction trafficking and regulation

Gene Expression

Generic Transcription Pathway

GP1b-IX-V activation signalling

GPCR downstream signaling

GPCR ligand binding

GPVI-mediated activation cascade


Hexose transport

Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Integration of energy metabolism

Integrin alphaIIb beta3 signaling

Integrin cell surface interactions

Interferon alpha/beta signaling

Interferon gamma signaling

Interferon Signaling

Interleukin-1 processing

Interleukin-1 signaling

Interleukin-3, 5 and GM-CSF signaling

Intrinsic Pathway for Apoptosis


L1CAM interactions

MAPK targets/ Nuclear events mediated by MAP kinases

Membrane Trafficking

Metabolism of carbohydrates

Metabolism of lipids and lipoproteins

Metabolism of nitric oxide

Metabolism of nucleotides

Metabolism of porphyrins

Metabolism of proteins

Metabolism of vitamins and cofactors

Metabolism of water-soluble vitamins and cofactors

Mitotic G1-G1/S phases

Mitotic G2-G2/M phases

mRNA Capping

mRNA Editing

Muscle contraction


NCAM signaling for neurite out-growth

Nephrin interactions

Netrin-1 signaling

Neurotransmitter Clearance In The Synaptic Cleft

Neurotransmitter Release Cycle

Neurotransmitter uptake and Metabolism In Glial Cells

NGF signalling via TRKA from the plasma membrane

Nucleosome assembly

Passive Transport by Aquaporins

Peroxisomal lipid metabolism

Phase 1 – Functionalization of compounds

Phase II conjugation

Platelet Adhesion to exposed collagen

Platelet Aggregation (Plug Formation)

Platelet homeostasis

Post-translational modification: synthesis of GPI-anchored proteins

Post-translational protein modification

Processing of Capped Intron-Containing Pre-mRNA

Processing of Capped Intronless Pre-mRNA

Protein folding

Rap1 signalling

Regulation of Apoptosis

Regulation of beta-cell development

Regulation of DNA replication

Regulation of mitotic cell cycle

Regulatory RNA pathways

Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.

Response to elevated platelet cytosolic Ca2+

RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways

RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription

RNA Polymerase II Transcription

Semaphorin interactions

Signal amplification

Signal regulatory protein (SIRP) family interactions

Signaling by EGFR

Signaling by FGFR

Signaling by GPCR

Signaling by Insulin receptor

Signaling by Interleukins

Signaling by PDGF

Signaling by Rho GTPases

Signaling by Robo receptor

Signaling by VEGF

Signaling by Wnt

SLC-mediated transmembrane transport

Synthesis of DNA

Synthesis, Secretion, and Deacylation of Ghrelin

TCR signaling

Telomere Maintenance

Thrombin signalling through proteinase activated receptors (PARs)


Transmembrane transport of small molecules

Transmission across Chemical Synapses

Transmission across Electrical Synapses

Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds

Transport of inorganic cations/anions and amino acids/oligopeptides

Transport of vitamins, nucleosides, and related molecules

tRNA Aminoacylation

Unfolded Protein Response

Signalling by NGF

Opioid Signalling

Nucleotide Excision Repair

Cellular responses to stress

Mitotic Prometaphase

PIP3 activates AKT signaling

Mitotic Prophase

Activation of Chaperone Genes by ATF6-alpha

TAK1 activates NFkB by phosphorylation and activation of IKKs complex

Growth hormone receptor signaling

HIV Life Cycle

Deadenylation-dependent mRNA decay

Abnormal metabolism in phenylketonuria

Cell-Cell communication

Regulation of Water Balance by Renal Aquaporins


Gastrin-CREB signalling pathway via PKC and MAPK

Botulinum neurotoxicity

Elastic fibre formation

Activation of Chaperone Genes by XBP1(S)

Influenza Infection

Potassium Channels

Iron uptake and transport


ISG15 antiviral mechanism

Interleukin-7 signaling

Signal Transduction

Signaling by NODAL

Platelet activation, signaling and aggregation

Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)

Prolactin receptor signaling

MHC class II antigen presentation

Aquaporin-mediated transport

Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes


Influenza Life Cycle

Host Interactions of HIV factors

GABA synthesis, release, reuptake and degradation

Regulation of Cholesterol Biosynthesis by SREBP (SREBF)

O2/CO2 exchange in erythrocytes

DAG and IP3 signaling

M Phase

Cytosolic Iron-sulfur Cluster Assembly

Peptide hormone biosynthesis

Transport of Glycerol from Adipocytes to the Liver by Aquaporins

Metabolism of amino acids and derivatives

DAP12 interactions

Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate

Developmental Biology


Meiotic Recombination


Latent infection of Homo sapiens with Mycobacterium tuberculosis

Neuronal System

Mitochondrial Iron-Sulfur Cluster Biogenesis

Extracellular matrix organization

Interleukin-6 signaling

Adaptive Immune System

Activation of Gene Expression by SREBP (SREBF)

Antiviral mechanism by IFN-stimulated genes

Degradation of collagen

Trafficking and processing of endosomal TLR

Nonsense-Mediated Decay

Collagen formation

Abacavir transport and metabolism

Signaling by SCF-KIT

Signaling by Hippo

Metabolism of non-coding RNA

Innate Immune System

Mitochondrial Protein Import

Signaling by NOTCH2

Fcgamma receptor (FCGR) dependent phagocytosis

Signaling by NOTCH1

Signaling by NOTCH4

Signaling by NOTCH3

HIV Infection

alpha-linolenic (omega3) and linoleic (omega6) acid metabolism

Collagen biosynthesis and modifying enzymes

Cytokine Signaling in Immune system

Regulation of Hypoxia-inducible Factor (HIF) by Oxygen

Incretin Synthesis, Secretion, and Inactivation

Metabolism of Angiotensinogen to Angiotensins

Signaling by NOTCH

Meiotic Synapsis

Interleukin-2 signaling

Regulation of mRNA Stability by Proteins that Bind AU-rich Elements

Ubiquinol biosynthesis

RAF/MAP kinase cascade

Insulin Processing

SRP-dependent cotranslational protein targeting to membrane

YAP1- and WWTR1 (TAZ)-stimulated gene expression


Glycerophospholipid biosynthesis

Inositol phosphate metabolism

Signaling by TGF-beta Receptor Complex

Glycosaminoglycan metabolism

Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes

Cell Cycle

Signaling by the B Cell Receptor (BCR)

PI Metabolism

Energy dependent regulation of mTOR by LKB1-AMPK

Metabolism of steroid hormones and vitamin D

O-linked glycosylation of mucins

Transcriptional Regulation of White Adipocyte Differentiation

MyD88-independent cascade

Activation of Genes by ATF4

Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell

Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer

Cellular response to hypoxia

Mitotic Metaphase and Anaphase

Phospholipid metabolism

Fc epsilon receptor (FCERI) signaling

Signaling by BMP

MyD88:Mal cascade initiated on plasma membrane

PTM: gamma carboxylation, hypusine formation and arylsulfatase activation

Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways

Lipid digestion, mobilization, and transport

Mitotic Telophase/Cytokinesis

The citric acid (TCA) cycle and respiratory electron transport

ER to Golgi Transport

MyD88 dependent cascade initiated on endosome

Activation of Matrix Metalloproteinases

Reversible Hydration of Carbon Dioxide

Host Interactions with Influenza Factors

S Phase

Degradation of beta-catenin by the destruction complex

Degradation of the extracellular matrix

Toll-Like Receptors Cascades

Visual phototransduction

Translocation of GLUT4 to the Plasma Membrane


Peptide hormone metabolism

Signaling by ERBB2

Signaling by ERBB4


Immune System

Binding and Uptake of Ligands by Scavenger Receptors

M/G1 Transition

Pre-NOTCH Expression and Processing

Syndecan interactions

Sphingolipid metabolism

Signaling by NOTCH1 in Cancer

WNT ligand biogenesis and trafficking

Signaling by Activin

MAP kinase activation in TLR cascade


Cytosolic sensors of pathogen-associated DNA

Class I MHC mediated antigen processing & presentation

Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)

Assembly of collagen fibrils and other multimeric structures

Regulation of Insulin-like Growth Factor (IGF) Transport and Uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)


MyD88 cascade initiated on plasma membrane